Nucleuspulposus相关论文
Transcription factor FoxA2 is crucial regulator of type II collagen induced adipose-derived mesenchy
Objective: FoxA transcription factors are essential for the development of dorsal axial structures and required for form......
Evaluation of CD24as a marker to rapidly define the mesenchymal stem cell phenotype and its differen
Background Recent studies have indicated that human nucleus pulposus contain mesenchymal stromal cells(NP-MSCs).However,......
Objective: Naringin,a famous flavanone glycoside of citrus fruits,is demonstrated to have pharmacological capabilities,i......
Type Ⅱ collagen ameliorates adipose-derived mesenchymal stem cell differentiating towards nucleus pu
Objective: Nucleus pulposus degeneration triggers intervertebral disc degeneration initially.Type Ⅱ collagen is the maj......
Factor-Inhibiting Hypoxia-Inducible Factor-1modulates Catabolic Effects of Tumor Necrosis Factor-alp
Bcakground: In degenerative intervertebral disc,the hypoxia inducible factors(HIFs)are the important factors involved in......
Bcakground: Both hypoxia and the marked increase of inflammatory cytokines are the common hallmarks of intervertebral di......
Background:Histone deacetylase inhibitors (HDACi), a new class of anti-cancer agents, have recently been reported to exh......
Background Intervertebral disc degeneration(IDD)is a common cause of low back pain.Patients who fail expectant treatment......
The Experimental Study On The Effect Of Instrumentation Autoguided Growing Rod System On Growth Plat
[Objective] To evaluate effect of auto-guided growing rod system on spinal growth though animal experiment. [Methods] 6 ......
Different apoptosis pathways involves in rabbit nucleus pulposus cell apoptosis induced by different
Overload pressure induces cell apoptosis plays a role in IVD degeneration.To investigate the two main pathways of the ap......
NOTOCHORDALA CELL STIMULATES MESENCHYMAL STEM CELL PROLIFERATION AND DIFFERENTION TOWARD NUCLEUS PUL
Objective To isolate and coculture notochordal cells(NC)and mesenchymal stem cells(MSCs)from New Zealand rabbit immature......
Survivin is re-expressed in disc degeneration disease and is required for degenerated nucleus pulpos
Survivin is a unique inhibitor of apoptosis which occurs within degenerated human nucleus pulposus(NP)cells frequently.I......
Objective:The aim of this study was to systematically investigate the role of necroptosis in compression-induced rat nuc......
Aim:To explore the effect of inflammatory cytokines on a disintegrins and metalloproteinase with thrombospondin motifs 7......
SIRT1 expression is refractory to hypoxia and inflammatory cytokines in nucleus pulposus cells: Nove
Backgrounds:Hypoxia and a marked increase in inflammatory cytokines are common hallmarks of intervertebral disc degenera......
Impaired regulation of chondroitin sulfate biosynthesis in human intervertebral disc degeneration: r
Objective: Intervertebral disc degeneration (IDD) is characterized by loss of water content.Chondroitin sulfate (CS) is ......
Dysregulated miR-127-5p contributes to extracellular matrix degradation and activation of TGF-β by t
Intervertebral disc degeneration(IDD)is associated with extracellular matrix(ECM)degradation.Dysregulated expression of ......
Survivin is re-expressed in disc degeneration disease and is required for degenerated nucleus pulpos
Survivin is a unique inhibitor of apoptosis which occurs within degenerated human nucleus pulposus (NP) cells frequently......
An Essential Role of Integrin A2b1in Mediating Nucleus PulposusCells Differentiated from Adipose-Der
Background and Objective: Integrins are receptors in cell surface that straddle the cell membrane by one transmembrane h......
Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells,a
Bcakground: Proteoglycan degradation contributing to the pathogenesis of intervertebral disc(IVD)degeneration is induced......
Protective effect of 17β-estradiol on rat nucleus pulposus cells against apoptosis induced by hydrog
It has been suggested that intervertebral disc(IVD)cell apoptosis playing a key role in promoting disc degeneration,and ......
TIGAR mediates the inhibitory role of hypoxia on ROS production and apoptosis in rat nucleus pulposu
Objective Hypoxia has been shown to inhibit reactive oxygen species (ROS) production in nucleus pulposus (NP) cells.The ......
Zonal variations in actin organization in the nucleus pulposus of human intervertebral disc in norma
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Evaluation of CD24 as a marker to rapidly define the mesenchymal stem cell phenotype and its differe
...
目的 研究慢病毒介导生存素基因（Lentivirus-Survivin）对早、晚期反分化人椎间盘髓核细胞的生物学效应。方法应用组织块法分离培养人......
Effect of electroacupuncture on E-prostanoid 2 expression in the spinal cord in rats with neuropathi
OBJECTIVE:To observe the effect of electroacupuncture (EA) treatment on the expression of E-prostanoid 2 (EP2) in the sp......
Gua Sha attenuates thermal hyperalgesia and decreases proinflammatory cytokine expression in serum i
OBJECTIVE:To investigate the analgesic effect of Gua Sha and its underlying mechanism in rats with noncompressive lumbar......
[目的]观察平面培养体系内人退变椎间盘髓核细胞的形态及活性变化.[方法]收集20例人退变椎间盘髓核,分离髓核细胞行平面培养,倒置......
[目的]探讨脱细胞软骨基质多孔支架复合PKH26标记的山羊髓核细胞体内异位构建组织工程髓核的可行性.[方法]制备脱细胞软骨基质来源......
[目的]设计构建一种新型组织工程椎间盘的复合支架材料,为组织工程椎间盘的实验研究奠定基础.[方法]应用冷冻干燥、化学交联等组织......
椎间盘退变是造成下背部疼痛的重要原因,其发病机制复杂,应用髓核假体可以较好的模拟自身正常的髓核组织,在临床上取得了较好的短......
目的 探讨微创手术治疗腰椎间盘突出症的临床疗效.方法 50例腰椎间盘突出患者,25例患者采用后路显微内镜下椎间盘切除术治疗,25例......
